AdeR protein regulates adeABC expression by binding to a direct-repeat motif in the intercistronic spacer
نویسندگان
چکیده
منابع مشابه
Mechanistic insight into how multidrug resistant Acinetobacter baumannii response regulator AdeR recognizes an intercistronic region
AdeR-AdeS is a two-component regulatory system, which controls expression of the adeABC efflux pump involved in Acinetobacter baumannii multidrug resistance. AdeR is a response regulator consisting of an N-terminal receiver domain and a C-terminal DNA-binding-domain. AdeR binds to a direct-repeat DNA in the intercistronic region between adeR and adeABC. We demonstrate a markedly high affinity b...
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ژورنال
عنوان ژورنال: Microbiological Research
سال: 2016
ISSN: 0944-5013
DOI: 10.1016/j.micres.2015.11.010